Medullary
News and Site Updates Archive 2009/09/15A positive attitude may not solve all your problems, but it will annoy enough people to make it worth the effort. - Herm Albright 15 Sep '09 - On 20 August 2009, Abdelbaset Ali Mohmed Al Megrahi,
the convicted Lockerbie bomber, was released by the Cabinet Secretary for Justice in Scotland, Kenny
MacAskil, on compassionate grounds due to terminal prostate cancer. But does Megrahi really have terminal cancer? Was he released because of an oil deal between Britain and Colonel Gaddafi's
son? Was he hailed as a hero back home in Libya? There is SO MUCH more to the story than what is generally reported. I urge you to
go read it. Basically, I gather Megrahi was released because he was innocent and "the truth" coming out during
the appeal could prove embarrassing to Britain and the US. Of course there were oil and arms deals under way with Libya; but had Megrahi proceeded with his appeal, some 600 pages of new and deliberately
suppressed evidence would have set the seal on his innocence and given more than a glimpse of how and why he was stitched up for the benefit of "strategic interests." (As an example, most of the staff
of the US embassy in Moscow who had reserved seats on Pan Am flights from Frankfurt cancelled their bookings when they were alerted by US intelligence that a terrorist attack was planned.) Wouldn't life
be a LOT simpler if lying invariably made your face turn bright red? Courts would likely convene in a darkness lit by coloured bulbs to "protect everyone's rights". Stairway to Heaven: The Haiku Trail in the mountains of Oahu, Hawai'i Warmer seas, increased tropical rainfall, fewer subtropical clouds, stronger trade winds — all seem connected to the sun's roughly 11-year cycle, whose ebbs and flows in sunspots result in solar output variations. Since variations are only 0.2 watt per metre2 that's too little to explain effects. However, ozone in the tropical stratosphere traps slightly more heat as increased ultraviolet sunlight warms its surroundings. This causes global ozone production to increase by 2%, affecting stratospheric circulation, which alters tropospheric circulation, which then changes wind patterns near the ground. The reason this is important is that the sun should have sunspots by now but still doesn't. Do we need global warming to stave off an ice age which could cause the deaths of billions - or is the sunspot thing a fluke that will go away tomorrow or in a decade and if global warming isn't reined in, resulting changes could cause the deaths of billions? (Or is it somewhere in between?) To acquire more knowledge about this situation would appear to be useful... In 1874, the first US zoo opened to great fanfare in Philadelphia. With bands playing and flags fluttering, thousands arrived to see exotic wallabies, kangaroos, bears, and an Indian elephant. In the 75 years following, others rushed in as American zookeepers engaged in animal "stamp collecting" - the goal: to acquire as many species as possible, housing them, often alone, in simple cages - one of this, one of that, one of the next thing, just so you could see what a tiger looked like. But in 1979, Kiki the gorilla stepped into a different world. Held captive for years in concrete and bars at Woodland Park Zoo in Seattle, he now had a lush exhibit - grass and stream designed to resemble wild Africa where he briefly lived. Gorillas loved it and so did visitors. But it caused a major problem - sometimes the animals hid from view. An estimated 15 million people died worldwide in 2002 due to bacterial infections that could not be treated by available drugs, according to figures from the World Health Organization. In the US,
more than 300,000 people die each year from infectious diseases such as influenza and pneumonia; many of these deaths are caused by drug-resistant bacteria. Governments could provide financial incentives to drug companies to develop new antibiotics - something drug
companies don't normally find to be lucrative because these take years to develop, yet can only be prescribed for a short time before becoming obsolete when bacteria change to survive... Over the past 4
years, pandemic preparations have focused on responding to worst case scenarios so we responded to the H1N1 outbreak as an unfolding disaster - some countries erected port of entry quarantines while others
advised against non-essential travel to affected areas and closed schools and businesses. But pandemic A/H1N1
is significantly different than the pandemic predicted. Pandemic A/H1N1 virus isn't a new subtype but the same subtype as seasonal H1N1, around since 1977. Furthermore, a lot of people are
likely immune. The 1918 pandemic was a type 1 epidemic: severe disease affecting many people, while SARS was a type 2 epidemic: infecting few, mostly severe disease. The
H1N1 pandemic may prove to be a type 3 epidemic: affecting many, mostly mild. Public health responses not calibrated to the threat may be perceived as alarmist, eroding public trust and
resulting in the public ignoring important warnings when serious epidemics happen in the future. It occurs to me that certain drug companies stand to make a sizable profit from vaccines they produce for
this mild pandemic (some countries are even mandating vaccinations). Perhaps these big pharmaceuticals will use some of that money to develop a few critical antibiotics that the human race
desperately needs. (Maybe that was even the agreement beforehand - with this "designated pandemic" a way to divert big money to those companies in this cash-strapped environment.)
We want our roads, bridges, tunnels, masstransit rails, dams, pipelines, sewers, canals and transmission
cables to last. When they don’t, the consequences range from irritation and anxiety to panic and disaster. But if we design infrastructure to endure forever, we may create another kind of
problem. New York bridges such as the George Washington and the Bayonne, both more than 70 years old, were built before computers were around to calculate the minimum amount of materials budget-crunched
contractors could get away with. Back then, cautious engineers simply heaped excess mass onto the bridges they imagined. These bridges are so overbuilt, traffic’s like an ant on an
elephant, By contrast, the Minneapolis bridge, half the age of those robust older spans, was already known to be crumbling before it failed. At the time of its collapse, 4 of 8 lanes were closed
for repairs to roadway deck and several weakened steel joints, the extent of deterioration hidden from public view behind tarpaulins. Although no official cause of the calamity has been identified by the
National Transportation Safety Board, the added weight of construction materials and cement trucks to evening rush hour traffic was apparently enough to break the I-35W bridge’s back. That only 13 people
died was considered miraculous. But should we risk building something enormously costly that might soon become obsolete? What if our search for energy-efficient, next-generation transportation produces a
vehicle — say a hovercraft — that renders unnecessary not only energy-gobbling transmissions and friction-prone rubber tires but possibly even roads themselves and for that matter tunnels and bridges
as well?
On 22 July 1975, Stanley J Forman was a photographer for an American newspaper, the Boston Herald, when a police scanner
picked up an emergency: “Fire on Marlborough Street!” 19-year-old Diana Bryant and her 2-year-old goddaughter Tiare Jones were on the fire escape awaiting rescue. Unfortunately, the ladder knocked
the fire escape from the wall as the two were stepping onto it and Diana fell to her death (Tiare lived only because Diana broke her fall). Stanley had been poised to get a photo of the rescue but
instead found himself with a photo of two people in mid-air, falling helplessly. This photo (click once to view) garnered Stanley Forman a Pulitzer Prize. Why? Because he didn't get distracted and remembered to press the shutter? I am reminded of
another
prize-winning photo (click once to view) - that taken by Kevin Carter of a vulture waiting for a starving child to die and also the photo (click once to view) of Omayra
Sanchez, a Columbian 13-year-old trapped due to a volcanic eruption up to her neck in water by concrete and other debris pinning her legs. Omayra took 3 days to succumb to gangrene and
hypothermia. What makes these photos all prize winners? Because they're so horrifying that they're memorable and because they prompted change in the situations that allowed them to
occur. Nevertheless, this reminds me of Kate Winslet: Not only did she appear in an episode of Extras as herself starring in a holocaust movie because she believed that is what it would take for
her to bring an Oscar statue home, she then went and starred in a holocaust movie which earned her an Oscar. Sometimes established prizes lose focus on their original purpose and are awarded for
emotional shock value rather than a reasoned and impartial judgment of worth. This can be quite unfair to artists because later works, unhonoured, never quite measure up though they may, in fact, be
technically superior.
How can one escape a dilemma in which multiple individuals acting in their own rational self-interest can ultimately
destroy a shared limited resource — even when it's clear this serves no one in the long run? Each family has a house and a small plot of land to grow vegetables. In addition, a large, common area
is used by all villagers to graze their livestock. Each villager has a cow or two to provide the family with milk. The common area is large enough to support the entire village - but the village
begins to grow; families get larger and get an extra cow. New families move in and suddenly the common is threatened; it's being overgrazed. Grass is consumed so fast, there isn't enough time for
it to replenish itself before rains erode the topsoil. No cow has quite enough to eat and they all give less milk than before. If this overuse continues, there'll be a slow, sure decrease in the
number of animals it can support until, finally, it's useless for grazing. From the point of view of an individual villager, since he needs the milk from his 2 or 3 cows even if they produce less than
before, less beats nothing. Besides, how much difference will it make if only he shows restraint in use of the common? So, commons problems are marked by conflicts between individual and
collective interests and between short-term and long-term interests. Unfortunately, we're now dealing with a tragedy of global commons. Which brings up the point of how connected global transportation, power, communications and financial markets
have become. Each component of each sector assesses risk for its particular piece under the assumption that the rest of the system will continue as always even if one small contribution goes off the
rails. We now know, however, about the possibility of cascading "knock on" failures. We don't yet know how to assess the risk for them, nor how best to quickly stop the spread of damage once
begun - but recognising the problem is an important step. Failing to deal with systemic risk will create a world that is not only uncertain, but also unjust, in that individual firms can generate
immense profits by taking risks that everyone else ends up bearing as well.
Music is a sure way to influence human emotions. Musical elements even convey the emotional content in
our speech. Studies show that babies too young to understand words can interpret a long tone and a descending pitch as soothing and a short tone as inhibiting. We use legato (long tones) with
babies to calm them and staccato to order them to stop. Approval has a rising tone; soothing is decreasing in tone. We add musical features to speech to influence the affective state of the
baby. Bark out, "PLAY WITH IT!" and the baby will freeze. Voice, intonation pattern, and musicality matter more than words. People look at animal communication in terms of conveying
information – "I'm hungry" or "I'm afraid" - but it's much more than that. A cellist with the National Symphony Orchestra composed music using specific features in the calls of cotton-top tamarin
monkeys (in other words, he made "monkey music"). It induced a relatively long-term change in behaviour in them (they relaxed and ate more). Similarities in communications between
monkeys and people suggest deep evolutionary roots for musical elements of speech. (Does the instant availability of exactly the relaxing music you want to hear help explain the epidemic of obesity if
it proves that relaxing music induces humans to eat more as
well?)... 4 out of 5 people see nothing wrong with
stealing from their workplace. More than half think it acceptable for a carer to persuade an elderly person to rewrite their will. A fascinating insight into Britain's "moral compass" also
found that 1 in 3 have downloaded music illegally and 13% have shoplifted. The findings, from an online study of more than 15,000 people, suggest that the typical Briton is less honest and more confused
than most people realise. It also shows that the concept of honesty varies hugely from person to person. (Always remember - the world you live in is the one YOU help create! If you want to
live in a world full of honest people, you must start by being as honest yourself as you are able.)
The complement response is a primordial part of the immune system that attacks and destroys the organs and vascular lining of people who have been deprived of oxygen for prolonged periods. It kicks in after the victim has been revived, in what is known as a reperfusion injury. Cells deprived of oxygen often undergo biochemical changes, essentially marking themselves for death. When blood flow and oxygen are restored, these changes trigger the complement cascade. It works slowly but unrelentingly, killing soldiers, infants or heart attack victims over the course of days. It exists in almost identical form in everything from seagulls to starfish. To find a way to manipulate this pharmacologically has been like a search for the Holy Grail. Two researchers working in neighbouring labs noticed a similarity in the structure of the molecules one was using in experiments and the other was studying. They wondered what would happen if they introduced the astrovirus shell one was studying into an assay routinely used by the other to assess complement activation. The rest, as they say, is history... A mixture of 4 artificial sweeteners (aspartame, acesulfame K, cyclamate and saccharin) was concocted to match the taste of real sugar as closely as possible. And the sugary and artificial drinks were administered on different days - making it harder for the tasters to notice any difference between the two. Subjects often guessed wrong on which drink was which. They didn't know - yet functional MRI scans revealed consistent differences in how their brains responded. Both sugar and non-caloric sweeteners activate a brain region called the amygdala, which signals sensory pleasure. But only the sugared drink turned on a cherry-sized nugget of brain tissue in a region called the caudate. That little nugget seems to represent an unconscious perception of calories - assessed quite separately from taste. Feliz: In the immortal words of Jeff Bridges, "Nice marmot." FastFreddy: I remember telling an American once that I liked Marmite on toast for breakfast. She replied, "Don't they eat their own !@#$?" and I knew there was a disconnect somewhere. An actress who is late for an audition is driving around and around and there's no parking anywhere. What a strange illusion it is to suppose that beauty is goodness. - Leo Tolstoy For other updates click "Home" (for the latest) or "Next" (for older) below |